Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)

To date over 400 HUCB transplants have been reported from different centers. It has been suggested that there is a reduced graft‐versus‐host‐disease (GVHD) with HUCB compared to bone marrow transplantation. Since cytokine production by a cell is an indication of the cells function it is important to...

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Main Authors: J. A. García Vela, I. Delgado, R. Bornstein, B. Alvarez, M. C. Auray, I. Martin, F. Oña, F. Gilsanz
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2000/572952
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author J. A. García Vela
I. Delgado
R. Bornstein
B. Alvarez
M. C. Auray
I. Martin
F. Oña
F. Gilsanz
author_facet J. A. García Vela
I. Delgado
R. Bornstein
B. Alvarez
M. C. Auray
I. Martin
F. Oña
F. Gilsanz
author_sort J. A. García Vela
collection DOAJ
description To date over 400 HUCB transplants have been reported from different centers. It has been suggested that there is a reduced graft‐versus‐host‐disease (GVHD) with HUCB compared to bone marrow transplantation. Since cytokine production by a cell is an indication of the cells function it is important to determinate the differences between APB and HUCB with respect to production of these soluble factors. Our aim was to analyse the intracellular cytokine production by HUCB and APB T lymphocytes with and emphasize on their possible role in GVHD.
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language English
publishDate 2000-01-01
publisher Wiley
record_format Article
series Analytical Cellular Pathology
spelling doaj-art-a15f27f7aa1c45a7b06704c287ac70d62025-02-03T06:44:48ZengWileyAnalytical Cellular Pathology0921-89121878-36512000-01-01202-3939810.1155/2000/572952Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)J. A. García Vela0I. Delgado1R. Bornstein2B. Alvarez3M. C. Auray4I. Martin5F. Oña6F. Gilsanz7Department of Hematology, Hospital Universitario de Getafe, Madrid, SpainDepartment of Hematology, Hospital Universitario de Getafe, Madrid, SpainDepartment of Hematology, Hospital Universitario 12 de Octubre, Madrid, Universidad Complutense, Madrid, SpainDepartment of Hematology, Hospital Universitario de Getafe, Madrid, SpainDepartment of Hematology, Hospital Universitario 12 de Octubre, Madrid, Universidad Complutense, Madrid, SpainDepartment of Hematology, Hospital Universitario de Getafe, Madrid, SpainDepartment of Hematology, Hospital Universitario de Getafe, Madrid, SpainDepartment of Hematology, Hospital Universitario 12 de Octubre, Madrid, Universidad Complutense, Madrid, SpainTo date over 400 HUCB transplants have been reported from different centers. It has been suggested that there is a reduced graft‐versus‐host‐disease (GVHD) with HUCB compared to bone marrow transplantation. Since cytokine production by a cell is an indication of the cells function it is important to determinate the differences between APB and HUCB with respect to production of these soluble factors. Our aim was to analyse the intracellular cytokine production by HUCB and APB T lymphocytes with and emphasize on their possible role in GVHD.http://dx.doi.org/10.1155/2000/572952
spellingShingle J. A. García Vela
I. Delgado
R. Bornstein
B. Alvarez
M. C. Auray
I. Martin
F. Oña
F. Gilsanz
Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)
Analytical Cellular Pathology
title Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)
title_full Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)
title_fullStr Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)
title_full_unstemmed Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)
title_short Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB)
title_sort comparative intracellular cytokine production by in vitro stimulated t lymphocytes from human umbilical cord blood hucb and adult peripheral blood apb
url http://dx.doi.org/10.1155/2000/572952
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