Gut microbiota derived metabolite trimethylamine N-oxide influences prostate cancer progression via the p38/HMOX1 pathway

Gut microbiota derived metabolite trimethylamine N-oxide influences prostate cancer progression via the p38/HMOX1 pathway

BackgroundProstate cancer was the fourth most diagnosed cancer worldwide in 2022. Radical treatments and androgen deprivation therapy benefit newly diagnosed patients but impact quality of life, often leading to castration-resistant prostate cancer. Short-term dietary changes significantly affect th...

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Bibliographic Details
Main Authors: Yuhua Zhou, Jing Lv, Shengkai Jin, Chaowei Fu, Bo Liu, Yang Shen, Menglu Li, Yuwei Zhang, Ninghan Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
trimethylamine N-oxide
gut microbiota
prostate cancer
HMOX1
high-choline diet
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1526051/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1526051/full

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