Spray-Dried Griseofulvin-Lactose Matrix for Enhanced Solubility Using a Spray-Drying Biochemical Process

Griseofulvin (GF) is a hydrophobic drug with a low solubility. In order to improve the solubility of GF, which has low water solubility, this report uses the spray-drying technique to prepare complexes with lactose to promote the solubility and oral bioavailability of GF. The solution samples were s...

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Bibliographic Details
Main Authors: Tian Lan, Jie Yang, Zhi-jie Yang, Hong-wen Wu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2022/8372048
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