In Situ Tumor Vaccination Using Lipid Nanoparticles to Deliver Interferon-β mRNA Cargo

In Situ Tumor Vaccination Using Lipid Nanoparticles to Deliver Interferon-β mRNA Cargo

<i>Background:</i> In situ cancer vaccination is a therapeutic approach that involves stimulating the immune system in order to generate a polyclonal, anti-tumor response against an array of tumor neoantigens. Traditionally, in situ vaccination approaches have utilized adenoviral vectors...

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Bibliographic Details
Main Authors: Kenji Kimura, Aidan Aicher, Emma Niemeyer, Phurin Areesawangkit, Caitlin Tilsed, Karen P. Fong, Tyler E. Papp, Steven M. Albelda, Hamideh Parhiz, Jarrod D. Predina
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Vaccines
Subjects:
in situ vaccination
intratumoral immunotherapy
interferon
lipid nanoparticles
Online Access:https://www.mdpi.com/2076-393X/13/2/178
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https://www.mdpi.com/2076-393X/13/2/178

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