Analysis of changes in the genome of the Omsk hemorrhagic fever virus (Flaviviridae: <i>Orthoflavivirus</i>) during laboratory practices for virus preservation

Analysis of changes in the genome of the Omsk hemorrhagic fever virus (Flaviviridae: <i>Orthoflavivirus</i>) during laboratory practices for virus preservation

Introduction. Omsk hemorrhagic fever (OHF) is a severe disease identified in the 1940s in Western Siberia, Russia. Disease is caused by the OHF virus, which belongs to the genus Orthoflavivirus. The purpose of the work. Analysis of changes in the genome associated with the isolation of OHF virus...

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Bibliographic Details
Main Authors: Zhanna S. Tyulko, Artem V. Fadeev, Aleksei G. Vasilenko, Ekaterina A. Gradoboeva, Valerii V. Yakimenko, Andrey B. Komissarov
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2024-12-01
Series:Вопросы вирусологии
Subjects:
omsk hemorrhagic fever virus
ohf virus adaptation to the mouse organism
discriminant analysis
linked nucleotide substitutions
rate of substitutions occurrence
phylogenetic analysis
Online Access:https://virusjour.crie.ru/jour/article/viewFile/16686/944
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