The Key Role and Mechanism of Oxidative Stress in Hypertrophic Cardiomyopathy: A Systematic Exploration Based on Multi-Omics Analysis and Experimental Validation

The Key Role and Mechanism of Oxidative Stress in Hypertrophic Cardiomyopathy: A Systematic Exploration Based on Multi-Omics Analysis and Experimental Validation

Hypertrophic cardiomyopathy (HCM), characterised by abnormal ventricular thickening, involves complex mechanisms including gene mutations, calcium dysregulation, mitochondrial dysfunction, and oxidative stress. Oxidative stress plays a pivotal role in the progression of HCM by mediating cardiomyocyt...

Full description

Saved in:
Bibliographic Details
Main Authors: Sijie Zhang, Tianzhi Li, Shiyi Sun, Yujiao Jiang, Yuxin Sun, Yan Meng
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antioxidants
Subjects:
hypertrophic cardiomyopathy
oxidative stress
drug prediction
molecular docking
Online Access:https://www.mdpi.com/2076-3921/14/5/557
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2076-3921/14/5/557

Similar Items