Dominant follicle-targeted nanocarriers for GH delivery to alleviate premature ovarian insufficiency

Dominant follicle-targeted nanocarriers for GH delivery to alleviate premature ovarian insufficiency

Premature ovarian insufficiency (POI) is characterized by ovarian functional damage, leading to infertility and severe complications. Current treatment is merely to relieve the clinical symptoms by hormone supplementation. Growth hormone (GH) shows efficacy in restoring ovarian function. However, GH...

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Bibliographic Details
Main Authors: Shao Yang, Yawei Sun, Wei Luo, Xiaofeng Zhou, Xiao Gu, Wenzhe Zhang, Huashan Zhu, Wenjia Wu, Xueying Wu, Mengru Yu, Shan Wang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Materials Today Bio
Subjects:
Premature ovarian insufficiency (POI)
Growth hormone (GH)
Zeolitic imidazolate framework-8 (ZIF8)
Dominant follicles
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425005009
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