Optogenetically Activatable MLKL as a Standalone Functional Module for Necroptosis and Therapeutic Applications in Antitumoral Immunity

Abstract Necroptosis plays a crucial role in the progression of various diseases and has gained substantial attention for its potential to activate antitumor immunity. However, the complex signaling networks that regulate necroptosis have made it challenging to fully understand its mechanisms and tr...

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Main Authors: Da‐Hye Jeong, Seokhwi Kim, Han‐Hee Park, Kyoung‐Jin Woo, Jae‐Il Choi, Minji Choi, Jisoo Shin, So Hyun Park, Myung‐Wook Seon, Dakeun Lee, Jong‐Ho Cha, You‐Sun Kim
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
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Online Access:https://doi.org/10.1002/advs.202412393
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