CD8α marks a Mycobacterium tuberculosis-reactive human NK cell population with high activation potential

Abstract Natural Killer (NK) cells can recognize and kill Mycobacterium tuberculosis (Mtb)-infected cells in vitro, however their role after natural human exposure has not been well-studied. To identify Mtb-responsive NK cell populations, we analyzed the peripheral blood of healthy household contact...

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Main Authors: Nezar Mehanna, Atul Pradhan, Rimanpreet Kaur, Theodota Kontopoulos, Barbara Rosati, David Carlson, Nai-Kong V. Cheung, Hong Xu, James Bean, Katharine C. Hsu, Jean-Benoit Le Luduec, Charles Kyriakos Vorkas
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-98367-4
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