Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress
IntroductionThis study examined the influence of Spirulina platensis, ochratoxin A (OTA), and their combination on growth, antioxidant status, liver and kidney functions, immunity, and carcass traits of broiler chickens.Methods160 unsexed 1-day broiler chicks were divided into four treatment groups,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2024.1532353/full |
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| author | Ayman S. Salah Mahmoud S. El-Tarabany Marwa Mostafa Rania Samir Zaki Mahmoud M. Azzam Omnia I. El Euony Mahmoud Alagawany Antonia Lestingi Ahmed A. Elolimy Mahmoud Madkour Ahmed Fotouh |
| author_facet | Ayman S. Salah Mahmoud S. El-Tarabany Marwa Mostafa Rania Samir Zaki Mahmoud M. Azzam Omnia I. El Euony Mahmoud Alagawany Antonia Lestingi Ahmed A. Elolimy Mahmoud Madkour Ahmed Fotouh |
| author_sort | Ayman S. Salah |
| collection | DOAJ |
| description | IntroductionThis study examined the influence of Spirulina platensis, ochratoxin A (OTA), and their combination on growth, antioxidant status, liver and kidney functions, immunity, and carcass traits of broiler chickens.Methods160 unsexed 1-day broiler chicks were divided into four treatment groups, each consisting of 4 replications of 10 chicks. The duration of this study was six weeks, during which the experimental groups were organized as follows: G1 consumed a basal diet (control), G2 consumed a basal diet treated with OTA at a level of 1 mg/kg of diet, G3 consumed a basal diet treated with Spirulina platensis at a level of 1 g/kg of diet, G4 consumed a basal diet treated with OTA at a level of 1 mg/kg of diet and Spirulina platensis at a level of 1 g/kg diet.Results and discussionThe results illustrated that OTA-contaminated feed resulted in a significant elevation in total cholesterol, triglyceride, low- and very low density lipoprotein, and malondialdehyde, along with a significant reduction in antioxidant status and immunological response. On the other hand, Spirulina supplementation significantly enhanced performance performance (body weight, body weight gain and feed conversion ratio). Lipid profile was significantly decreased by Spirulina supplementation. Antioxidant activity (superoxide dismutase, catalase, total antioxidant capacity, and glutathione peroxidase) of broilers exposed to OTA was significantly increased by Spirulina supplementation. Finally, supplementing Spirulina platensis in broiler chickens fed on OTA contaminated diet attenuated the harmful effects of OTA, while improving the growth performance, antioxidant activity, lipid profile, and immune response of broiler chickens. |
| format | Article |
| id | doaj-art-a0eb360272a64e249aa4730b190a36c5 |
| institution | Kabale University |
| issn | 2297-1769 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj-art-a0eb360272a64e249aa4730b190a36c52025-01-29T06:45:36ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-01-011110.3389/fvets.2024.15323531532353Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stressAyman S. Salah0Mahmoud S. El-Tarabany1Marwa Mostafa2Rania Samir Zaki3Mahmoud M. Azzam4Omnia I. El Euony5Mahmoud Alagawany6Antonia Lestingi7Ahmed A. Elolimy8Mahmoud Madkour9Ahmed Fotouh10Department of Animal Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, New Valley University, El-Kharga, EgyptDepartment of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Sharkia, EgyptDepartment of Pathology, Faculty of Veterinary Medicine, Benha University, Toukh, EgyptDepartment of Food Hygiene, Safety and Technology, Faculty of Veterinary Medicine, New Valley University, El Kharga, EgyptDepartment of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi ArabiaDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, EgyptPoultry Department, Faculty of Agriculture, Zagazig University, Zagazig, EgyptDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, ItalyDepartment of Integrative Agriculture, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Abu Dhabi, United Arab Emirates0Animal Production Department, National Research Centre, Giza, Egypt1Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, New Valley University, El Kharga, EgyptIntroductionThis study examined the influence of Spirulina platensis, ochratoxin A (OTA), and their combination on growth, antioxidant status, liver and kidney functions, immunity, and carcass traits of broiler chickens.Methods160 unsexed 1-day broiler chicks were divided into four treatment groups, each consisting of 4 replications of 10 chicks. The duration of this study was six weeks, during which the experimental groups were organized as follows: G1 consumed a basal diet (control), G2 consumed a basal diet treated with OTA at a level of 1 mg/kg of diet, G3 consumed a basal diet treated with Spirulina platensis at a level of 1 g/kg of diet, G4 consumed a basal diet treated with OTA at a level of 1 mg/kg of diet and Spirulina platensis at a level of 1 g/kg diet.Results and discussionThe results illustrated that OTA-contaminated feed resulted in a significant elevation in total cholesterol, triglyceride, low- and very low density lipoprotein, and malondialdehyde, along with a significant reduction in antioxidant status and immunological response. On the other hand, Spirulina supplementation significantly enhanced performance performance (body weight, body weight gain and feed conversion ratio). Lipid profile was significantly decreased by Spirulina supplementation. Antioxidant activity (superoxide dismutase, catalase, total antioxidant capacity, and glutathione peroxidase) of broilers exposed to OTA was significantly increased by Spirulina supplementation. Finally, supplementing Spirulina platensis in broiler chickens fed on OTA contaminated diet attenuated the harmful effects of OTA, while improving the growth performance, antioxidant activity, lipid profile, and immune response of broiler chickens.https://www.frontiersin.org/articles/10.3389/fvets.2024.1532353/fullbroilersOTASpirulina platensisameliorationmitigationgrowth |
| spellingShingle | Ayman S. Salah Mahmoud S. El-Tarabany Marwa Mostafa Rania Samir Zaki Mahmoud M. Azzam Omnia I. El Euony Mahmoud Alagawany Antonia Lestingi Ahmed A. Elolimy Mahmoud Madkour Ahmed Fotouh Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress Frontiers in Veterinary Science broilers OTA Spirulina platensis amelioration mitigation growth |
| title | Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress |
| title_full | Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress |
| title_fullStr | Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress |
| title_full_unstemmed | Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress |
| title_short | Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress |
| title_sort | impact of dietary spirulina on performance antioxidant status carcass traits and pathological alteration in broilers exposed to ochratoxin a stress |
| topic | broilers OTA Spirulina platensis amelioration mitigation growth |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2024.1532353/full |
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