Integrating bioinformatics and metabolomics to identify potential biomarkers of hypertensive nephropathy

Integrating bioinformatics and metabolomics to identify potential biomarkers of hypertensive nephropathy

Abstract Hypertensive nephropathy (HN), caused by long-term poorly controlled hypertension, is the second common cause of end-stage renal disease after diabetes mellitus, but the pathogenesis of HN is unclear. The purpose of this study was to identify the biological pathways involved in the progress...

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Bibliographic Details
Main Authors: Kezhen Yang, Pingna Zhang, Xiaofeng Ding, Gong Yu, Jipeng Liu, Yi Yang, Jianqiao Fang, Qingguo Liu, Lu Zhang, Jianhua Li, Fangchao Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Bioinformatic
Metabolomics
Hypertensive nephropathy
Bile acid
Bile acid metabolism
Online Access:https://doi.org/10.1038/s41598-025-89601-0
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https://doi.org/10.1038/s41598-025-89601-0

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