Mesomycoplasma hyopneumoniae lipoprotein Mhp390 serves as a plasminogen receptor mediating extracellular matrix degradation and respiratory epithelial cells injury

Mesomycoplasma hyopneumoniae lipoprotein Mhp390 serves as a plasminogen receptor mediating extracellular matrix degradation and respiratory epithelial cells injury

Abstract The destruction of the respiratory barrier caused by Mesomycoplasma (Mycoplasma) hyopneumoniae plays a pivotal role in facilitating secondary infections by other respiratory pathogens. However, the pathogenesis of M. hyopneumoniae breaching the respiratory barrier to establish infection rem...

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Main Authors: Wei Liu, Liying Ye, Keli Yang, Xingyu Yan, Ting Gao, Fangyan Yuan, Rui Guo, Zewen Liu, Chang Li, Qiong Wu, Jiajia Zhu, Yongxiang Tian, Bo Tang, Qiqi Song, Danna Zhou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Veterinary Research
Subjects:
Mesomycoplasma (Mycoplasma) hyopneumoniae
Mhp390
plasminogen
interaction
respiratory barrier invasion
Online Access:https://doi.org/10.1186/s13567-025-01551-7
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https://doi.org/10.1186/s13567-025-01551-7

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