Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms

Detection of clustered microcalcifications (MCs) in mammograms represents a significant step towards successful detection of breast cancer since their existence is one of the early signs of cancer. In this paper, a new framework that integrates Bayesian classifier and a pattern synthesizing scheme f...

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Main Authors: Imad Zyout, Ikhlas Abdel-Qader, Christina Jacobs
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2009/767805
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author Imad Zyout
Ikhlas Abdel-Qader
Christina Jacobs
author_facet Imad Zyout
Ikhlas Abdel-Qader
Christina Jacobs
author_sort Imad Zyout
collection DOAJ
description Detection of clustered microcalcifications (MCs) in mammograms represents a significant step towards successful detection of breast cancer since their existence is one of the early signs of cancer. In this paper, a new framework that integrates Bayesian classifier and a pattern synthesizing scheme for detecting microcalcification clusters is proposed. This proposed work extracts textural, spectral, and statistical features of each input mammogram and generates models of real MCs to be used as training samples through a simplified learning phase of the Bayesian classifier. Followed by an estimation of the classifier's decision function parameters, a mammogram is segmented into the identified targets (MCs) against background (healthy tissue). The proposed algorithm has been tested using 23 mammograms from the mini-MIAS database. Experimental results achieved MCs detection with average true positive (sensitivity) and false positive (specificity) of 91.3% and 98.6%, respectively. Results also indicate that the modeling of the real MCs plays a significant role in the performance of the classifier and thus should be given further investigation.
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issn 1687-4188
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spelling doaj-art-a06cf45024084f9ba366c5111254eba22025-02-03T01:25:35ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962009-01-01200910.1155/2009/767805767805Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital MammogramsImad Zyout0Ikhlas Abdel-Qader1Christina Jacobs2Department of Electrical and Computer Engineering, Western Michigan University, MI 49008, USADepartment of Electrical and Computer Engineering, Western Michigan University, MI 49008, USARadiology Department, Bronson Methodist Hospital, Kalamazoo, MI 49007, USADetection of clustered microcalcifications (MCs) in mammograms represents a significant step towards successful detection of breast cancer since their existence is one of the early signs of cancer. In this paper, a new framework that integrates Bayesian classifier and a pattern synthesizing scheme for detecting microcalcification clusters is proposed. This proposed work extracts textural, spectral, and statistical features of each input mammogram and generates models of real MCs to be used as training samples through a simplified learning phase of the Bayesian classifier. Followed by an estimation of the classifier's decision function parameters, a mammogram is segmented into the identified targets (MCs) against background (healthy tissue). The proposed algorithm has been tested using 23 mammograms from the mini-MIAS database. Experimental results achieved MCs detection with average true positive (sensitivity) and false positive (specificity) of 91.3% and 98.6%, respectively. Results also indicate that the modeling of the real MCs plays a significant role in the performance of the classifier and thus should be given further investigation.http://dx.doi.org/10.1155/2009/767805
spellingShingle Imad Zyout
Ikhlas Abdel-Qader
Christina Jacobs
Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms
International Journal of Biomedical Imaging
title Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms
title_full Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms
title_fullStr Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms
title_full_unstemmed Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms
title_short Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms
title_sort bayesian classifier with simplified learning phase for detecting microcalcifications in digital mammograms
url http://dx.doi.org/10.1155/2009/767805
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