Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy

Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy

Abstract Nothing is known about the potential implication of gut microbiota in skeletal muscle disorders. Here, we provide evidence that fecal microbiota composition along with circulating levels of short‐chain fatty acids (SCFAs) and related metabolites are altered in the mdx mouse model of Duchenn...

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Main Authors: Hilal Kalkan, Ester Pagano, Debora Paris, Elisabetta Panza, Mariarosaria Cuozzo, Claudia Moriello, Fabiana Piscitelli, Armita Abolghasemi, Elisabetta Gazzerro, Cristoforo Silvestri, Raffaele Capasso, Andrea Motta, Roberto Russo, Vincenzo Di Marzo, Fabio Arturo Iannotti
Format: Article
Language:English
Published: Springer Nature 2023-01-01
Series:EMBO Molecular Medicine
Subjects:
autophagy
duchenne muscular dystrophy
endocannabinoid system
gut microbiota
short‐chain fatty acids
Online Access:https://doi.org/10.15252/emmm.202216225
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https://doi.org/10.15252/emmm.202216225

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