Revisiting the use of CK7 and CK20 immunohistochemical stains in pathological diagnoses

Abstract Background Cytokeratin-7 (keratin-7; CK7) and cytokeratin-20 (keratin-20; CK20) have been among the most widely used markers in pathology for prediction of tumor site of origin or classification. However, with the increased availability of newer and more specific biomarkers and molecular te...

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Bibliographic Details
Main Authors: Bangchen Wang, Diana M. Cardona, Jiaoti Huang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-025-01638-x
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