Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure
Anaemia is a common comorbidity in patients with heart failure (HF) and is associated with more severe symptoms and increased mortality. The aim of this study was to evaluate haemodynamic profiles of HF patients with respect to the presence of reduced left ventricular ejection fraction (LVEF) and an...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/9371967 |
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| author | Paweł Krzesiński Agata Galas Grzegorz Gielerak Beata Uziębło-Życzkowska |
| author_facet | Paweł Krzesiński Agata Galas Grzegorz Gielerak Beata Uziębło-Życzkowska |
| author_sort | Paweł Krzesiński |
| collection | DOAJ |
| description | Anaemia is a common comorbidity in patients with heart failure (HF) and is associated with more severe symptoms and increased mortality. The aim of this study was to evaluate haemodynamic profiles of HF patients with respect to the presence of reduced left ventricular ejection fraction (LVEF) and anaemia. Methods and Results. Haemodynamic status was evaluated in 97 patients with acute decompensated HF. Impedance cardiography, echocardiography, and N-terminal probrain natriuretic peptide (NT-proBNP) results were analysed. The study group was stratified into four subgroups according to LVEF (<40% vs ≥40%) and the presence of anaemia (haemoglobin <13.0 g/dL in men and <12.0 g/dL in women). Thoracic fluid content was higher (p=0.037) in anaemic subjects, while no significant relation between anaemia and NYHA was observed. Anaemic subjects with LVEF ≥ 40% were distinguished from those with LVEF < 40% by significantly higher stroke index (p=0.002), Heather index (p=0.014), and acceleration index (p=0.047). Patients with reduced LVEF and anaemia presented the highest NT-proBNP (p=0.003). Conclusions. In acute decompensated HF, anaemia is related with fluid overload, relatively higher cardiac systolic performance but no clinical benefit in patients with preserved/midrange LVEF, and increased left ventricular tension, fluid overload, and impaired cardiac systolic performance in patients with reduced LVEF. |
| format | Article |
| id | doaj-art-9fe62dcb02e64d16a4a944d7b387fe4c |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
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| series | Cardiology Research and Practice |
| spelling | doaj-art-9fe62dcb02e64d16a4a944d7b387fe4c2025-02-03T01:05:00ZengWileyCardiology Research and Practice2090-80162090-05972020-01-01202010.1155/2020/93719679371967Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart FailurePaweł Krzesiński0Agata Galas1Grzegorz Gielerak2Beata Uziębło-Życzkowska3Department of Cardiology and Internal Diseases, Military Institute of Medicine, Szaserów Street 128, 04-141 Warsaw, PolandDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Szaserów Street 128, 04-141 Warsaw, PolandDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Szaserów Street 128, 04-141 Warsaw, PolandDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Szaserów Street 128, 04-141 Warsaw, PolandAnaemia is a common comorbidity in patients with heart failure (HF) and is associated with more severe symptoms and increased mortality. The aim of this study was to evaluate haemodynamic profiles of HF patients with respect to the presence of reduced left ventricular ejection fraction (LVEF) and anaemia. Methods and Results. Haemodynamic status was evaluated in 97 patients with acute decompensated HF. Impedance cardiography, echocardiography, and N-terminal probrain natriuretic peptide (NT-proBNP) results were analysed. The study group was stratified into four subgroups according to LVEF (<40% vs ≥40%) and the presence of anaemia (haemoglobin <13.0 g/dL in men and <12.0 g/dL in women). Thoracic fluid content was higher (p=0.037) in anaemic subjects, while no significant relation between anaemia and NYHA was observed. Anaemic subjects with LVEF ≥ 40% were distinguished from those with LVEF < 40% by significantly higher stroke index (p=0.002), Heather index (p=0.014), and acceleration index (p=0.047). Patients with reduced LVEF and anaemia presented the highest NT-proBNP (p=0.003). Conclusions. In acute decompensated HF, anaemia is related with fluid overload, relatively higher cardiac systolic performance but no clinical benefit in patients with preserved/midrange LVEF, and increased left ventricular tension, fluid overload, and impaired cardiac systolic performance in patients with reduced LVEF.http://dx.doi.org/10.1155/2020/9371967 |
| spellingShingle | Paweł Krzesiński Agata Galas Grzegorz Gielerak Beata Uziębło-Życzkowska Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure Cardiology Research and Practice |
| title | Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure |
| title_full | Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure |
| title_fullStr | Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure |
| title_full_unstemmed | Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure |
| title_short | Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure |
| title_sort | haemodynamic effects of anaemia in patients with acute decompensated heart failure |
| url | http://dx.doi.org/10.1155/2020/9371967 |
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