Extramedullary disease is associated with severe toxicities following B-cell maturation antigen CAR T-cell therapy in multiple myeloma

Extramedullary disease is associated with severe toxicities following B-cell maturation antigen CAR T-cell therapy in multiple myeloma

Extramedullary disease (EMD) in multiple myeloma (MM) is associated with poor outcomes following B-cell maturation antigen (BCMA)-targeted CAR-T therapy, yet its impact on treatment-related toxicity remains unclear. This study evaluates the impact of active EMD on toxicity, efficacy, and survival i...

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Main Authors: Andrew J. Portuguese, Emily C. Liang, Jennifer J. Huang, Yein Jeon, Danai Dima, Rahul Banerjee, Mary Kwok, Kara I. Cicero, Alexandre V. Hirayama, Ryan Basom, Christy Khouderchah, Mazyar Shadman, Lawrence Fong, Andrew J. Cowan, Jordan Gauthier
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-06-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12122
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https://haematologica.org/article/view/12122

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