Blood immunomap for prediction of responses to anti-PD-1 immunotherapy in metastatic non-small cell lung cancer

Blood immunomap for prediction of responses to anti-PD-1 immunotherapy in metastatic non-small cell lung cancer

Summary: The identification of circulating predictors of response to ICB therapy is vital as very few of them meet the demands of the clinic. Herein, by using high-dimensionality mass cytometry, we designed a blood immunomap in metastatic NSCLC individuals who underwent anti-PD-1 treatment. We ident...

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Main Authors: Maria Semitekolou, Nikolaos Paschalidis, Domenico Lo Tartaro, Aikaterini Tsitsopoulou, Panagiota Stamou, Alexandros Mavroudis, Effrosyni Markaki, Athina Varveri, Ioannis Morianos, Matthieu Lavigne, Charalampos Fotsitzoudis, Sofia Magkouta, Konstantina Dede, Ioannis Kalomenidis, Konstantinos Samitas, Konstantinos Potaris, Andrea Cossarizza, Dimitrios Mavroudis, Sara De Biasi, Panayiotis Verginis
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:iScience
Subjects:
Cancer
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422501065X
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http://www.sciencedirect.com/science/article/pii/S258900422501065X

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