Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children
Purpose. To investigate the effects of topical brimonidine 0.15% instillation on conjunctival injection after strabismus surgery in children. Methods. We retrospectively analyzed 63 Korean children who underwent strabismus surgery for intermittent exotropia. Patients received topical brimonidine 0.1...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2021/5574194 |
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| author | Dong Hyun Kim Hee Kyung Yang Sang Beom Han Jeong-Min Hwang |
| author_facet | Dong Hyun Kim Hee Kyung Yang Sang Beom Han Jeong-Min Hwang |
| author_sort | Dong Hyun Kim |
| collection | DOAJ |
| description | Purpose. To investigate the effects of topical brimonidine 0.15% instillation on conjunctival injection after strabismus surgery in children. Methods. We retrospectively analyzed 63 Korean children who underwent strabismus surgery for intermittent exotropia. Patients received topical brimonidine 0.15% after surgery for up to 4 weeks. Conjunctival injection was objectively assessed using a software that automatically scored the region of interest from the image of the bulbar conjunctiva. Conjunctival injection scores were compared with those of the control group who were not prescribed topical brimonidine. Results. The mean scores of conjunctival injection after rectus muscle recession and resection were significantly lower in the brimonidine group than the controls at 4 weeks after surgery (P=0.008 and 0.046, respectively). There was no significant difference in intraocular pressure between the two groups. No adverse effects, such as dry mouth, fatigue/drowsiness, headache, sedation, hypotension, or bradycardia, were reported. Conclusions. Administration of topical brimonidine 0.15% after strabismus surgery is efficacious and safe in reducing postoperative conjunctival injection. |
| format | Article |
| id | doaj-art-9fbe2bca3625433489b3d3eeb0a9faae |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-9fbe2bca3625433489b3d3eeb0a9faae2025-02-03T06:46:15ZengWileyJournal of Ophthalmology2090-004X2090-00582021-01-01202110.1155/2021/55741945574194Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in ChildrenDong Hyun Kim0Hee Kyung Yang1Sang Beom Han2Jeong-Min Hwang3Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of KoreaDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of KoreaDepartment of Ophthalmology, Kangwon National University College of Medicine, Kangwon National University Hospital, Chuncheon, Kangwon, Republic of KoreaDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of KoreaPurpose. To investigate the effects of topical brimonidine 0.15% instillation on conjunctival injection after strabismus surgery in children. Methods. We retrospectively analyzed 63 Korean children who underwent strabismus surgery for intermittent exotropia. Patients received topical brimonidine 0.15% after surgery for up to 4 weeks. Conjunctival injection was objectively assessed using a software that automatically scored the region of interest from the image of the bulbar conjunctiva. Conjunctival injection scores were compared with those of the control group who were not prescribed topical brimonidine. Results. The mean scores of conjunctival injection after rectus muscle recession and resection were significantly lower in the brimonidine group than the controls at 4 weeks after surgery (P=0.008 and 0.046, respectively). There was no significant difference in intraocular pressure between the two groups. No adverse effects, such as dry mouth, fatigue/drowsiness, headache, sedation, hypotension, or bradycardia, were reported. Conclusions. Administration of topical brimonidine 0.15% after strabismus surgery is efficacious and safe in reducing postoperative conjunctival injection.http://dx.doi.org/10.1155/2021/5574194 |
| spellingShingle | Dong Hyun Kim Hee Kyung Yang Sang Beom Han Jeong-Min Hwang Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children Journal of Ophthalmology |
| title | Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children |
| title_full | Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children |
| title_fullStr | Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children |
| title_full_unstemmed | Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children |
| title_short | Effect of Topical Brimonidine 0.15% on Conjunctival Injection after Strabismus Surgery in Children |
| title_sort | effect of topical brimonidine 0 15 on conjunctival injection after strabismus surgery in children |
| url | http://dx.doi.org/10.1155/2021/5574194 |
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