Design and development of an aptamer targeting C-type lectin-like molecule-1 as a biomarker for acute myeloid leukemia: a SELEX approach

Design and development of an aptamer targeting C-type lectin-like molecule-1 as a biomarker for acute myeloid leukemia: a SELEX approach

Acute myeloid leukemia (AML), a hematologic malignancy, is an important public health issue. It is a result of the abnormal proliferation of immature myeloid cells. Despite advancements in diagnostic procedures, the early identification of AML remains a significant clinical challenge, marking a dist...

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Bibliographic Details
Main Authors: Yiwen Chen, Qinhang Li, Shifeng Lou, Hanqing Zeng, Shu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
aptamer
C-type lectin-like molecule-1
acute myeloid leukemia
SELEX
molecule
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1601453/full
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