Mossy fiber expression of αSMA in human hippocampus and its relevance to brain evolution and neuronal development

Mossy fiber expression of αSMA in human hippocampus and its relevance to brain evolution and neuronal development

Abstract α-Smooth muscle actin (αSMA) is best characterized as the building block of thin filaments in smooth muscle cells. We observed a clear αSMA immunolabeling in adult human hippocampal mossy fibers (MF), prompting us to explore this novel pattern in phylogenic and ontogenic perspectives in the...

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Main Authors: Tian Tu, Xiao-Lu Cai, Zhong-Ping Sun, Chen Yang, Juan Jiang, Lily Wan, Jia-Qi Ai, Yan Wang, Sidiki Coulibaly, Bei-Sha Tang, Jian Wang, Jian-Hong Wang, Yan Zhang, Xiao-Ping Wang, Ying Peng, Hua Wang, Aihua Pan, Xiao-Xin Yan, Ewen Tu, Qi-Lei Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Actin isoforms
Brain development
Mammalian evolution
Synaptoplasticity
Trisynaptic circuit
Online Access:https://doi.org/10.1038/s41598-025-00094-3
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https://doi.org/10.1038/s41598-025-00094-3

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