The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children

The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children

Abstract Background Chronic inflammation and its control are crucial to the responses of glomerular and renal tubular cells. This contributes to the pathogenic mechanisms and advancement of the disease in Alport syndrome. The study aimed to elucidate the role of cyclooxygenase-2, Interleukin 4, Plas...

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Main Authors: Moushira Zaki, Hisham A. Orban, Mohamed A. Shahba, Rehab S. I. Moustafa, Ahmed Adel, Fatina I. Fadel, Abeer Selim, Hala T. El-Bassyouni, Eman R. Youness
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Pediatrics
Subjects:
Alport syndrome
Cyclooxygenase-2
Interleukin 4
Plasminogen activating inhibitor 1
Prostaglandin E2
Online Access:https://doi.org/10.1186/s12887-025-05412-2
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https://doi.org/10.1186/s12887-025-05412-2

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