Identification of Transcriptomic Differences in Induced Pluripotent Stem Cells and Neural Progenitors from Amyotrophic Lateral Sclerosis Patients Carrying Different Mutations: A Pilot Study

Identification of Transcriptomic Differences in Induced Pluripotent Stem Cells and Neural Progenitors from Amyotrophic Lateral Sclerosis Patients Carrying Different Mutations: A Pilot Study

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neurons with a phenotypic and genetic heterogeneity and elusive molecular mechanisms. With the present pilot study, we investigated different genetic mutations (<i>C9orf72</i>, <i>TARDBP&...

Full description

Saved in:
Bibliographic Details
Main Authors: Chiara Sgromo, Martina Tosi, Cristina Olgasi, Fabiola De Marchi, Francesco Favero, Giorgia Venturin, Beatrice Piola, Alessia Cucci, Lucia Corrado, Letizia Mazzini, Sandra D’Alfonso, Antonia Follenzi
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
Amyotrophic lateral sclerosis
induced pluripotent stem cells
transcriptomic analysis
RNA-seq
neural progenitor cells
Online Access:https://www.mdpi.com/2073-4409/14/13/958
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2073-4409/14/13/958

Similar Items