Antibiotic cycling versus mixing: The difficulty of using mathematicalmodels to definitively quantify their relative merits

We ask the question Which antibiotic deployment protocols select best against drug-resistant microbes: mixing or periodic cycling? and demonstrate that the statistical distribution of the performances of both sets of protocols, mixing and periodic cycling, must have overlapping supports. In other w...

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Bibliographic Details
Main Authors: Robert E. Beardmore, Rafael Peña-Miller
Format: Article
Language:English
Published: AIMS Press 2010-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.923
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