High-grade non-muscle invasive urothelial carcinoma in dogs and humans share specific expression of integrin α5β1

High-grade non-muscle invasive urothelial carcinoma in dogs and humans share specific expression of integrin α5β1

ObjectiveUrothelial carcinoma (UC) accounts for more than 90% of all bladder cancers both in humans and dogs. Human and canine UC share many genetic mutations and tumor markers and clinical and therapeutic interventions. The unmet clinical needs are similar such as the early detection and treatment...

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Main Authors: Roberta Lucianò, Maurizio Colecchia, Francesca Sanvito, Irene Locatelli, Chiara Venegoni, Alessia Di Coste, Davide Danilo Zani, Angelica Stranieri, Chiara Giudice, Antonella Rigillo, Matteo Gambini, Francesco Montorsi, Andrea Salonia, Marco Moschini, Massimo Alfano
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
urothelial cancer
human
dog
integrin
marker
bladder
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1590073/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1590073/full

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