Subtle behavioral alterations in the spontaneous behaviors of MPTP mouse model of Parkinson’s disease

Abstract Midbrain dopamine (DA) neurons are essential for regulating movement, emotion, and reward, with their dysfunction closely linked to Parkinson’s disease (PD). While DA neurons in the substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) have known overlapping roles in behavio...

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Bibliographic Details
Main Authors: Hao Zhong, Kangrong Lu, Liping Wang, Wanshan Wang, Pengfei Wei, Xuemei Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03312-8
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