The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites

Signal-dependent transport into and out of the nucleus mediated by members of the importin (IMP) superfamily is crucial for eukaryotic function, with inhibitors targeting IMPα being of key interest as anti-infectious agents, including against the apicomplexan <i>Plasmodium</i> species an...

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Bibliographic Details
Main Authors: Sujata B. Walunj, Geetanjali Mishra, Kylie M. Wagstaff, Swati Patankar, David A. Jans
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/1/39
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