Gentamicin Induced Nephrotoxicity: The Role of Sex Hormones in Gonadectomized Male and Female Rats

Background. Gentamicin (GM) induced nephrotoxicity may be sex hormones related. The effects of sex hormones on GM induced nephrotoxicity in gonadectomized rats were investigated. Methods. Ovariectomized rats received 0.25, 0.5, or 1 mg/kg/week of estradiol (ES) alone or accompanied with 10 mg/kg/wee...

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Bibliographic Details
Main Authors: Fatemeh Eshraghi-Jazi, Ardeshir Talebi, Fatemeh Sadat Mirsaeedi, Sarina Ahmadian, Fatemeh Moslemi, Mehdi Nematbakhsh
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2016/5025097
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