COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant
Background. Post-COVID-19 nephropathies have been reported profusely in the literature with diverse pathophysiological mechanisms. To the best of our knowledge, this is the first report of transient distal (type 1) renal tubular acidosis (dRTA) in an infant with confirmed COVID-19. Case Presentation...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2022/5361305 |
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| author | Seyedeh-Kiana Razavi-Amoli Hamid Mohammadjafari Daniel Zamanfar Mohammad Reza Navaeifar Zahra Sadati-Lamradi Mohammad Sadegh Rezai |
| author_facet | Seyedeh-Kiana Razavi-Amoli Hamid Mohammadjafari Daniel Zamanfar Mohammad Reza Navaeifar Zahra Sadati-Lamradi Mohammad Sadegh Rezai |
| author_sort | Seyedeh-Kiana Razavi-Amoli |
| collection | DOAJ |
| description | Background. Post-COVID-19 nephropathies have been reported profusely in the literature with diverse pathophysiological mechanisms. To the best of our knowledge, this is the first report of transient distal (type 1) renal tubular acidosis (dRTA) in an infant with confirmed COVID-19. Case Presentation. We describe a 32-day-old female with diarrhea and fever without respiratory complaints. Her weight, height, and head circumference were normal for age. The primary lab test showed leukocytosis, neutrophilia, elevated inflammatory markers, and non-anion-gap metabolic acidosis. Real-time polymerase chain reaction (RT-PCR) and elevated SARS-CoV-2 immunoglobulin M confirmed COVID-19, while echocardiography and spiral chest computed tomography scan were normal. Intravenous fluid therapy and supportive care were initiated. Blood culture was positive for Klebsiella pneumoniae. Amikacin and cefotaxime were ordered. Although diarrhea and dehydration gradually improved, venous blood gas still showed metabolic acidosis. Due to the alkaline urine and hypokalemic-hyperchloremic metabolic acidosis, dRTA was diagnosed. Notably, the patient dramatically responded to Shohl’s solution. Conclusions. Regarding the various manifestations of COVID-19, the possible association between dRTA and COVID-19 needs further investigation in children. |
| format | Article |
| id | doaj-art-9ec247e314c7496aaafa7cbd7eaef3d7 |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-9ec247e314c7496aaafa7cbd7eaef3d72025-02-03T05:53:39ZengWileyCase Reports in Infectious Diseases2090-66332022-01-01202210.1155/2022/5361305COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an InfantSeyedeh-Kiana Razavi-Amoli0Hamid Mohammadjafari1Daniel Zamanfar2Mohammad Reza Navaeifar3Zahra Sadati-Lamradi4Mohammad Sadegh Rezai5Student Research Committee School of MedicinePediatric Infectious Diseases Research CenterDiabetes Research CenterPediatric Infectious Diseases Research CenterPediatric Infectious Diseases Research CenterPediatric Infectious Diseases Research CenterBackground. Post-COVID-19 nephropathies have been reported profusely in the literature with diverse pathophysiological mechanisms. To the best of our knowledge, this is the first report of transient distal (type 1) renal tubular acidosis (dRTA) in an infant with confirmed COVID-19. Case Presentation. We describe a 32-day-old female with diarrhea and fever without respiratory complaints. Her weight, height, and head circumference were normal for age. The primary lab test showed leukocytosis, neutrophilia, elevated inflammatory markers, and non-anion-gap metabolic acidosis. Real-time polymerase chain reaction (RT-PCR) and elevated SARS-CoV-2 immunoglobulin M confirmed COVID-19, while echocardiography and spiral chest computed tomography scan were normal. Intravenous fluid therapy and supportive care were initiated. Blood culture was positive for Klebsiella pneumoniae. Amikacin and cefotaxime were ordered. Although diarrhea and dehydration gradually improved, venous blood gas still showed metabolic acidosis. Due to the alkaline urine and hypokalemic-hyperchloremic metabolic acidosis, dRTA was diagnosed. Notably, the patient dramatically responded to Shohl’s solution. Conclusions. Regarding the various manifestations of COVID-19, the possible association between dRTA and COVID-19 needs further investigation in children.http://dx.doi.org/10.1155/2022/5361305 |
| spellingShingle | Seyedeh-Kiana Razavi-Amoli Hamid Mohammadjafari Daniel Zamanfar Mohammad Reza Navaeifar Zahra Sadati-Lamradi Mohammad Sadegh Rezai COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant Case Reports in Infectious Diseases |
| title | COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant |
| title_full | COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant |
| title_fullStr | COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant |
| title_full_unstemmed | COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant |
| title_short | COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant |
| title_sort | covid 19 in coincidence with transient distal renal tubular acidosis in an infant |
| url | http://dx.doi.org/10.1155/2022/5361305 |
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