Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study
Aim. To evaluate the efficacy and safety of endoscopic submucosal tunnel dissection (ESTD) for resection of large superficial gastric lesions (SGLs). Methods. The clinicopathological records of patients performed with ESTD or endoscopic submucosal dissection (ESD) for SGLs between January 2012 and J...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/1419369 |
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| author | Xiuxue Feng Enqiang Linghu Ningli Chai Zhongsheng Lu Xiangdong Wang Ping Tang Jiangyun Meng Hong Du Hongbin Wang |
| author_facet | Xiuxue Feng Enqiang Linghu Ningli Chai Zhongsheng Lu Xiangdong Wang Ping Tang Jiangyun Meng Hong Du Hongbin Wang |
| author_sort | Xiuxue Feng |
| collection | DOAJ |
| description | Aim. To evaluate the efficacy and safety of endoscopic submucosal tunnel dissection (ESTD) for resection of large superficial gastric lesions (SGLs). Methods. The clinicopathological records of patients performed with ESTD or endoscopic submucosal dissection (ESD) for SGLs between January 2012 and January 2014 were retrospectively reviewed. 7 cases undergoing ESTD were enrolled to form the ESTD group. The cases were individually matched at a 1 : 1 ratio to other patients performed with ESD according to lesion location, ulcer or scar findings, resected specimen area, operation time and operators, and the matched cases constituting the ESD group. The treatment outcomes were compared between the two groups. Results. The mean specimen size was 46 mm. 10 lesions were located in the cardia and 4 lesions in the lesser curvature of the lower gastric body. En bloc resection was achieved for all lesions. The mean ESTD resection time was 69 minutes as against 87.7 minutes for the ESD (P=0.01). The mean resection speed was faster for ESTD than for ESD (18.86 mm2/min versus 13.76 mm2/min, P=0.03). There were no significant differences regarding the safety and curability during the endoscopic follow-up (mean 27 months). Conclusions. ESTD is effective and safe for the removal of SGLs and appears to be an optimal option for patients with large SGLs at suitable sites. |
| format | Article |
| id | doaj-art-9e84beec7ac8479d9374e50cfd55ea5a |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-9e84beec7ac8479d9374e50cfd55ea5a2025-02-03T01:24:18ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/14193691419369Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled StudyXiuxue Feng0Enqiang Linghu1Ningli Chai2Zhongsheng Lu3Xiangdong Wang4Ping Tang5Jiangyun Meng6Hong Du7Hongbin Wang8Department of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, ChinaAim. To evaluate the efficacy and safety of endoscopic submucosal tunnel dissection (ESTD) for resection of large superficial gastric lesions (SGLs). Methods. The clinicopathological records of patients performed with ESTD or endoscopic submucosal dissection (ESD) for SGLs between January 2012 and January 2014 were retrospectively reviewed. 7 cases undergoing ESTD were enrolled to form the ESTD group. The cases were individually matched at a 1 : 1 ratio to other patients performed with ESD according to lesion location, ulcer or scar findings, resected specimen area, operation time and operators, and the matched cases constituting the ESD group. The treatment outcomes were compared between the two groups. Results. The mean specimen size was 46 mm. 10 lesions were located in the cardia and 4 lesions in the lesser curvature of the lower gastric body. En bloc resection was achieved for all lesions. The mean ESTD resection time was 69 minutes as against 87.7 minutes for the ESD (P=0.01). The mean resection speed was faster for ESTD than for ESD (18.86 mm2/min versus 13.76 mm2/min, P=0.03). There were no significant differences regarding the safety and curability during the endoscopic follow-up (mean 27 months). Conclusions. ESTD is effective and safe for the removal of SGLs and appears to be an optimal option for patients with large SGLs at suitable sites.http://dx.doi.org/10.1155/2018/1419369 |
| spellingShingle | Xiuxue Feng Enqiang Linghu Ningli Chai Zhongsheng Lu Xiangdong Wang Ping Tang Jiangyun Meng Hong Du Hongbin Wang Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study Gastroenterology Research and Practice |
| title | Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study |
| title_full | Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study |
| title_fullStr | Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study |
| title_full_unstemmed | Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study |
| title_short | Endoscopic Submucosal Tunnel Dissection for Large Gastric Neoplastic Lesions: A Case-Matched Controlled Study |
| title_sort | endoscopic submucosal tunnel dissection for large gastric neoplastic lesions a case matched controlled study |
| url | http://dx.doi.org/10.1155/2018/1419369 |
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