Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa
Polyarteritis nodosa (PAN) is a rare systemic vasculitis that affects small to medium-sized arteries. It could affect any organ including the heart. However coronary artery involvements are very rare. We describe a young girl who presented following a histopathological diagnosis of PAN with acute ch...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2022/2175676 |
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| author | Lina Bayazeed Alaa Felimban Abdulsalam Alsaiad Fahd Alsufiani Jubran Alqanatish |
| author_facet | Lina Bayazeed Alaa Felimban Abdulsalam Alsaiad Fahd Alsufiani Jubran Alqanatish |
| author_sort | Lina Bayazeed |
| collection | DOAJ |
| description | Polyarteritis nodosa (PAN) is a rare systemic vasculitis that affects small to medium-sized arteries. It could affect any organ including the heart. However coronary artery involvements are very rare. We describe a young girl who presented following a histopathological diagnosis of PAN with acute chest pain, high serum troponin, and progressive ischemic changes in the electrocardiogram (ECG). Induction of remission of her disease was done with six-moths Cyclophosphamide infusions and pulse corticosteroids. In addition to anticoagulation and dual antithrombotic therapy, the disease remission was maintained with mycophenolate mofetil which helps in the recovery of coronary disease. Our case illustrates the serious cardiac involvement of PAN in a child that responded to intensive management. |
| format | Article |
| id | doaj-art-9e6f64d16376490ea7e1c68a8cb5071d |
| institution | Kabale University |
| issn | 2090-6897 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-9e6f64d16376490ea7e1c68a8cb5071d2025-02-03T01:22:57ZengWileyCase Reports in Rheumatology2090-68972022-01-01202210.1155/2022/2175676Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis NodosaLina Bayazeed0Alaa Felimban1Abdulsalam Alsaiad2Fahd Alsufiani3Jubran Alqanatish4King Saud Bin Abdulaziz University for Health SciencesKing Saud Bin Abdulaziz University for Health SciencesKing Saud Bin Abdulaziz University for Health SciencesKing Saud Bin Abdulaziz University for Health SciencesKing Saud Bin Abdulaziz University for Health SciencesPolyarteritis nodosa (PAN) is a rare systemic vasculitis that affects small to medium-sized arteries. It could affect any organ including the heart. However coronary artery involvements are very rare. We describe a young girl who presented following a histopathological diagnosis of PAN with acute chest pain, high serum troponin, and progressive ischemic changes in the electrocardiogram (ECG). Induction of remission of her disease was done with six-moths Cyclophosphamide infusions and pulse corticosteroids. In addition to anticoagulation and dual antithrombotic therapy, the disease remission was maintained with mycophenolate mofetil which helps in the recovery of coronary disease. Our case illustrates the serious cardiac involvement of PAN in a child that responded to intensive management.http://dx.doi.org/10.1155/2022/2175676 |
| spellingShingle | Lina Bayazeed Alaa Felimban Abdulsalam Alsaiad Fahd Alsufiani Jubran Alqanatish Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa Case Reports in Rheumatology |
| title | Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa |
| title_full | Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa |
| title_fullStr | Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa |
| title_full_unstemmed | Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa |
| title_short | Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa |
| title_sort | myocardial infarction in a 7 year old girl with polyarteritis nodosa |
| url | http://dx.doi.org/10.1155/2022/2175676 |
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