3-Hydroxybutyrate alleviates septic liver injury by promoting macrophage polarization from M1 to M2
Objective To investigate the therapeutic effects and underlying mechanisms of the metabolite 3- hydroxybutyrate (3HB) in a cecal ligation and puncture (CLP)-induced sepsis model in mice. Methods Male C57BL / 6J mice were divided into three groups: Sham, CLP, and CLP + 3HB groups. The survival rate,...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | zho |
Published: |
Lanzhou University Press
2024-12-01
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Series: | 生物医学转化 |
Subjects: | |
Online Access: | http://swyxzh.ijournals.cn/swyxzh/article/html/20240403 |
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