PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle

PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle

Introduction: Intramuscular adipose tissue (IMAT) is frequently formed in certain pathological conditions, such as biological aging, and ectopic fat accumulation leads to muscle weakness and a subsequent decline in physical function. Although mesenchymal progenitors (MPs) are present in postnatal sk...

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Bibliographic Details
Main Authors: Hiroki Iida, Minako Kawai-Takaishi, Yoshihiro Miyagawa, Yasuhiko Takegami, Akiyoshi Uezumi, Takeshi Honda, Shiro Imagama, Tohru Hosoyama
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Regenerative Therapy
Subjects:
Intramuscular adipose tissue
Mesenchymal progenitor
PDZRN3
Wnt signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425000185
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