Early posttranscriptional response to tetracycline exposure in a gram-negative soil bacterium reveals unexpected attenuation mechanism of a DUF1127 gene

Early posttranscriptional response to tetracycline exposure in a gram-negative soil bacterium reveals unexpected attenuation mechanism of a DUF1127 gene

The gram-negative, soil-dwelling plant symbiont Sinorhizobium meliloti shares its free-living habitat with antibiotic producers. To learn about early steps of its adaptation to antibiotics, we analysed transcriptome changes after 10 min exposure to subinhibitory amount of tetracycline (Tc). RNA-seq...

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Bibliographic Details
Main Authors: Jennifer A. F. Kothe, Till Sauerwein, Theresa Dietz, Robina Scheuer, Muhammad Elhossary, Susanne Barth-Weber, Jan Wähling, Konrad U. Förstner, Elena Evguenieva-Hackenberg
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:RNA Biology
Subjects:
Bacteria
Sinorhizobium
antibiotic exposure
transcription attenuation
upstream ORF
small genes
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2025.2521887
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https://www.tandfonline.com/doi/10.1080/15476286.2025.2521887

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