Amelioration of gut dysbiosis-induced cognitive deterioration by repeated administration of human clostridium butyricum: targeting intestinal and blood–brain barrier

Amelioration of gut dysbiosis-induced cognitive deterioration by repeated administration of human clostridium butyricum: targeting intestinal and blood–brain barrier

Abstract Background Disturbed intestinal integrity and increased permeability are linked to dysbiosis. This disruption involves GIT-related and unrelated diseases, such as neurological diseases. Intake of a high-fat diet (HFD) leads to an imbalance of gut microbiota and regression of bacteria produc...

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Bibliographic Details
Main Authors: Dalia Azmy Elberry, Maha Gamal, Zeinab Gawish, Esraa A. Hegazy, Sara Adel Hosny, Laila Ahmed Rashed, Marwa Nagi Mehesen, Asmaa Mohammed ShamsEldeen
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Dysbiosis
Microbiota
High-fat diet
Short-chain fatty acid
Clostridium butyricum
Tight junction protein
Online Access:https://doi.org/10.1186/s43094-025-00836-0
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