miR-1236-3p targets Toll-like receptor 4 to suppress the anti-Mycobacterium tuberculosis activity of macrophage

miR-1236-3p targets Toll-like receptor 4 to suppress the anti-Mycobacterium tuberculosis activity of macrophage

Summary: Mycobacterium tuberculosis (Mtb) modulates host innate immunity via Toll-like receptor 4 (TLR4), associated with the susceptibility to Mtb. Bioinformatics predicted miR-1236-3p could be a potential target for the 3′-UTR of the TLR4 gene. However, the clinical significance and underlying mec...

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Bibliographic Details
Main Authors: Yating Zhang, Jie Han, Qianwei Yang, Xiaogang Cui, Huiping Duan, Ting Wu, Changxin Wu, Li Xing, Qunqun Liu, Li Dong
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Immunology
Immune response
Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007837
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http://www.sciencedirect.com/science/article/pii/S2589004225007837

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