Exploring the role of diosgenin in modulating RUNX1 and HIPK2 transcription to mitigate Primary Sjögren's Syndrome

Background: Primary Sjögren's Syndrome (pSS) is a chronic autoimmune disease characterized by inflammation of the exocrine glands, resulting in symptoms like dry mouth and eyes. Despite existing symptomatic treatments, underlying immune dysregulation remains undefined. Diosgenin, a steroidal sa...

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Bibliographic Details
Main Authors: Yiwei Pan, Lunquan Wei, Han Liu, Fang Wang, Minhua Wang, Meijia Li, Pengfei Cheng, Xing Yan
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Immunobiology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525000440
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