T-cell immunity in the experimental autoimmune vasculitis rat model

T-cell immunity in the experimental autoimmune vasculitis rat model

ANCA-vasculitis (AAV) is a small-vessel vasculitis characterized by the presence of autoantibodies against proteinase-3 (PR3) or myeloperoxidase (MPO). The dynamics of the T-cell response within tissues is studied best in animal models. It was the aim to analyze the lesional T-cell dynamics in the e...

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Bibliographic Details
Main Authors: Ye Zeng, Erika Boschmann, Julia Kotte, Ming Sun, Lennart Hess, Sebastian Dolff, Tanja Hinkeldein, Janna Hagedorn, Robert Langer, Pieter van Paassen, Jan Damoiseaux, Jan Willem Cohen Tervaert, Oliver Witzke, Andreas Kribben, Benjamin Wilde
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Journal of Translational Autoimmunity
Subjects:
ANCA vasculitis
Th17 cells
Th1 cells
MPO
PR3
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909025000401
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