Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer
Ovarian cancer is the most fatal gynecologic malignancy. The incidence of ovarian cancer among female-to-male transsexuals receiving treatment with testosterone is unknown, and few cases have been reported in the literature. We report a recent case in our institution, a 23-year-old female-to-male tr...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2021/8861692 |
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| author | Cristina Ferreira João Fraga Célia Antunes Manuela Gonçalo Paulo Donato |
| author_facet | Cristina Ferreira João Fraga Célia Antunes Manuela Gonçalo Paulo Donato |
| author_sort | Cristina Ferreira |
| collection | DOAJ |
| description | Ovarian cancer is the most fatal gynecologic malignancy. The incidence of ovarian cancer among female-to-male transsexuals receiving treatment with testosterone is unknown, and few cases have been reported in the literature. We report a recent case in our institution, a 23-year-old female-to-male transsexual patient who received testosterone supplementation. The patient underwent a pelvic magnetic resonance imaging to study an ovarian complex cyst that revealed the presence of a bilateral ovarian tumor with imaging features of borderline serous tumor. These masses were surgically removed and the pathology report confirmed the diagnosis associated with noninvasive peritoneal implants and the presence of numerous androgen receptors in the tumor cells. Although there is still insufficient data to validate a direct correlation between hormonotherapy and ovarian cancer in these patients, this case may reinforce previous reports on this association and highlights the relevance of radiological follow-up and bilateral salpingo-oophorectomy as part of gender reassignment surgery. |
| format | Article |
| id | doaj-art-9d656fad45f2455e8c89b45c3a2fafee |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-9d656fad45f2455e8c89b45c3a2fafee2025-02-03T01:27:06ZengWileyCase Reports in Radiology2090-68622090-68702021-01-01202110.1155/2021/88616928861692Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian CancerCristina Ferreira0João Fraga1Célia Antunes2Manuela Gonçalo3Paulo Donato4Department of Radiology, University Centre Hospitals of Coimbra (CHUC), 3000-075 Coimbra, PortugalDepartment of Pathology, University Centre Hospitals of Coimbra (CHUC), 3000-075 Coimbra, PortugalDepartment of Radiology, University Centre Hospitals of Coimbra (CHUC), 3000-075 Coimbra, PortugalDepartment of Radiology, University Centre Hospitals of Coimbra (CHUC), 3000-075 Coimbra, PortugalDepartment of Radiology, University Centre Hospitals of Coimbra (CHUC), 3000-075 Coimbra, PortugalOvarian cancer is the most fatal gynecologic malignancy. The incidence of ovarian cancer among female-to-male transsexuals receiving treatment with testosterone is unknown, and few cases have been reported in the literature. We report a recent case in our institution, a 23-year-old female-to-male transsexual patient who received testosterone supplementation. The patient underwent a pelvic magnetic resonance imaging to study an ovarian complex cyst that revealed the presence of a bilateral ovarian tumor with imaging features of borderline serous tumor. These masses were surgically removed and the pathology report confirmed the diagnosis associated with noninvasive peritoneal implants and the presence of numerous androgen receptors in the tumor cells. Although there is still insufficient data to validate a direct correlation between hormonotherapy and ovarian cancer in these patients, this case may reinforce previous reports on this association and highlights the relevance of radiological follow-up and bilateral salpingo-oophorectomy as part of gender reassignment surgery.http://dx.doi.org/10.1155/2021/8861692 |
| spellingShingle | Cristina Ferreira João Fraga Célia Antunes Manuela Gonçalo Paulo Donato Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer Case Reports in Radiology |
| title | Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer |
| title_full | Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer |
| title_fullStr | Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer |
| title_full_unstemmed | Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer |
| title_short | Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer |
| title_sort | serous borderline tumor in transgender female to male individuals a case report of androgen receptor positive ovarian cancer |
| url | http://dx.doi.org/10.1155/2021/8861692 |
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