Fabrication of BMSCs-affinity peptide functionalized blended hyaluronic acid/polydopamine nanofibrous scaffolds to controlled Mg ion release and improved osteogenic differentiations for accelerating bone regeneration

Fabrication of BMSCs-affinity peptide functionalized blended hyaluronic acid/polydopamine nanofibrous scaffolds to controlled Mg ion release and improved osteogenic differentiations for accelerating bone regeneration

Abstract Bone regeneration requires innovative solutions to enhance osteogenic differentiation and support effective tissue repair. This study presents a novel approach to bone tissue engineering by developing peptide-functionalized nanofibrous scaffolds (NFS). The fabrication of a blended hyaluroni...

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Bibliographic Details
Main Authors: Jingzhe Zhang, Xinkun Wang, Xinbiao Fu, Ye Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Biological Engineering
Subjects:
Nanofibrous scaffolds
Osteogenic differentiation
Bone regeneration
Bone defects
In vivo rat model
Online Access:https://doi.org/10.1186/s13036-025-00529-5
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https://doi.org/10.1186/s13036-025-00529-5

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