ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis

Psoriasis is a common chronic, recurrent, immune-mediated inflammatory skin disease, which tends to occur in cold areas. Its pathogenesis is currently unclear. This study aims to screen differentially expressed genes in the psoriasis dataset, identify the central genes, detect the expression of cent...

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Main Authors: Sun Xianqi, Li Yuzhen, Yu Huiwen, Lin Jiaying, Wang Chen, Liu Quanlin, Bai Bingxue
Format: Article
Language:English
Published: De Gruyter 2025-01-01
Series:Frigid Zone Medicine
Subjects:
Online Access:https://doi.org/10.1515/fzm-2024-0022
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author Sun Xianqi
Li Yuzhen
Yu Huiwen
Lin Jiaying
Wang Chen
Liu Quanlin
Bai Bingxue
author_facet Sun Xianqi
Li Yuzhen
Yu Huiwen
Lin Jiaying
Wang Chen
Liu Quanlin
Bai Bingxue
author_sort Sun Xianqi
collection DOAJ
description Psoriasis is a common chronic, recurrent, immune-mediated inflammatory skin disease, which tends to occur in cold areas. Its pathogenesis is currently unclear. This study aims to screen differentially expressed genes in the psoriasis dataset, identify the central genes, detect the expression of central genes in psoriasis lesions of patients in the cold regions and then conduct further research.
format Article
id doaj-art-9d3f308aebeb4d99a334bee3ce9f77dc
institution Kabale University
issn 2719-8073
language English
publishDate 2025-01-01
publisher De Gruyter
record_format Article
series Frigid Zone Medicine
spelling doaj-art-9d3f308aebeb4d99a334bee3ce9f77dc2025-02-02T15:45:30ZengDe GruyterFrigid Zone Medicine2719-80732025-01-014422423210.1515/fzm-2024-0022ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasisSun Xianqi0Li Yuzhen1Yu Huiwen2Lin Jiaying3Wang Chen4Liu Quanlin5Bai Bingxue6Department of Dermetology, the Second Affiliated Hospital of Harbin Medical University, Harbin150001, ChinaDepartment of Dermetology, the Second Affiliated Hospital of Harbin Medical University, Harbin150001, ChinaDepartment of Dermetology, the Second Affiliated Hospital of Harbin Medical University, Harbin150001, ChinaDepartment of Dermetology, the Second Affiliated Hospital of Harbin Medical University, Harbin150001, ChinaDepartment of Dermetology, the Second Affiliated Hospital of Harbin Medical University, Harbin150001, ChinaHeilongjiang University of Chinese Medicine, Ministry of Education, Harbin150040, ChinaDepartment of Dermetology, the Second Affiliated Hospital of Harbin Medical University, Harbin150001, ChinaPsoriasis is a common chronic, recurrent, immune-mediated inflammatory skin disease, which tends to occur in cold areas. Its pathogenesis is currently unclear. This study aims to screen differentially expressed genes in the psoriasis dataset, identify the central genes, detect the expression of central genes in psoriasis lesions of patients in the cold regions and then conduct further research.https://doi.org/10.1515/fzm-2024-0022psoriasiskeratinocyte proliferationisg15wnt signaling pathway
spellingShingle Sun Xianqi
Li Yuzhen
Yu Huiwen
Lin Jiaying
Wang Chen
Liu Quanlin
Bai Bingxue
ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis
Frigid Zone Medicine
psoriasis
keratinocyte proliferation
isg15
wnt signaling pathway
title ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis
title_full ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis
title_fullStr ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis
title_full_unstemmed ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis
title_short ISG15 promotes M5-induced hacat cell proliferation through Wnt signaling in psoriasis
title_sort isg15 promotes m5 induced hacat cell proliferation through wnt signaling in psoriasis
topic psoriasis
keratinocyte proliferation
isg15
wnt signaling pathway
url https://doi.org/10.1515/fzm-2024-0022
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