Aberrant T-cell phenotypes in a cohort of patients with post-treatment Lyme disease

Aberrant T-cell phenotypes in a cohort of patients with post-treatment Lyme disease

Post-treatment Lyme Disease (PTLD) is a poorly understood complication of Borrelia burgdorferi infection with significant patient morbidity. Characterized by fatigue, generalized myalgias, and cognitive impairment, PTLD symptomatology closely resembles long COVID and other post-acute infection syndr...

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Main Authors: Alexander A. Girgis, Raffaello Cimbro, Ting Yang, Alison W. Rebman, Thelio Sewell, Daniela Villegas de Flores, Aarti Vadalia, William H. Robinson, Andrea L. Cox, Erika Darrah, Mark J. Soloski, John Aucott
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
post-treatment Lyme disease (PTLD)
flow cytometry
immune phenotyping
post-acute infection syndromes (PAIS)
cytokine profiling
T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1607619/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1607619/full

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