Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

ObjectiveThe efficacy of local anesthetics like ropivacaine in axillary brachial plexus blocks may be influenced by temperature, though its impact on the median effective concentration (EC50) remains unclear. This study aimed to determine the EC50 of ropivacaine at room temperature (RT, 23°C) and bo...

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Bibliographic Details
Main Authors: Alin Wang, Yunhao Shao, Yuling Zheng, Xiaoling Li, Bixin Huang, Ying Mai, Zhongqi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
media effective concentration
ropivacaine
temperature
nerve block
up-and-down method
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1591581/full
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