Spatial accuracy of dose delivery significantly impacts the planning target volume margin in linear accelerator-based intracranial stereotactic radiosurgery

Spatial accuracy of dose delivery significantly impacts the planning target volume margin in linear accelerator-based intracranial stereotactic radiosurgery

Abstract The impact of three-dimensional (3D) dose delivery accuracy of C-arm linacs on the planning target volume (PTV) margin was evaluated for non-coplanar intracranial stereotactic radiosurgery (SRS). A multi-institutional 3D starshot test using beams from seven directions was conducted at 22 cl...

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Main Authors: Yuta Takahashi, Riki Oshika, Rie Tachibana, Katsuyuki Shirai, Hiroshi Asakura, Masayoshi Miyazaki, Tomohiro Sagawa, Shinichi Takahashi, Tsunekazu Kuwae, Hironori Kojima, Shiro Nishiyama, Hikaru Nemoto, Yoshitomo Ishihara, Mariko Umeda, Kotaro Kijima, Daisuke Kobayashi, Keiji Suzuki, Yuki Nozawa, Kento Hoshida, Tomoki Kitagawa, Hiromitsu Endo, Yuki Matsunaga, Hiroya Itagaki, Mayumi Ishida, Shigeru Kanahara, Ryo Horita, Daisuke Hori, Hidenobu Tachibana
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
SRS
Linac
Three-dimensional dose delivery accuracy
Margin size
Gel dosimeter
Multi-institution
Online Access:https://doi.org/10.1038/s41598-025-87769-z
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