Phenotypic Timeline Kinetics, Integrative Networks, and Performance of T- and B-Cell Subsets Associated with Distinct Clinical Outcome of Severe COVID-19 Patients

Phenotypic Timeline Kinetics, Integrative Networks, and Performance of T- and B-Cell Subsets Associated with Distinct Clinical Outcome of Severe COVID-19 Patients

The present study aimed to evaluate the kinetics of the phenotypic profile and integrative networks of T/B-cells in severe COVID-19 patients, categorized according to disease outcome, during the circulation of the B.1.1.28 and B.1.1.33 SARS-CoV-2 strains in Brazil. Peripheral blood obtained at disti...

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Main Authors: Gabriela de Oliveira, Ismael Artur Costa-Rocha, Nani Oliveira-Carvalho, Tâmilla Mayane Alves Fidelis dos Santos, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Vitor Hugo Simões Miranda, Roberta Oliveira Prado, Agnes Antônia Sampaio Pereira, Clarice Carvalho Alves, Joaquim Pedro Brito-de-Sousa, Laise Rodrigues Reis, Christiane Costa-Pereira, Camila Pacheco Silveira Martins da Mata, Vanessa Egídio Silveira Almeida, Liliane Martins dos Santos, Gregório Guilherme Almeida, Lis Ribeiro do Valle Antonelli, Jordana Grazziela Coelho-dos-Reis, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Microorganisms
Subjects:
COVID-19
disease outcome
cellular memory
activation
exhaustion
Online Access:https://www.mdpi.com/2076-2607/12/11/2272
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