Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage
Introduction. Diffuse alveolar hemorrhage is a rare presentation of systemic lupus erythematosus. Early diagnosis and appropriate treatment can improve outcome. Case Report. An 18-year-old male presented with hemoptysis and respiratory distress requiring orotracheal intubation. Laboratory tests show...
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| Format: | Article |
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Wiley
2018-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2018/8218904 |
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| author | Omar Tolaymat Florentina Berianu |
| author_facet | Omar Tolaymat Florentina Berianu |
| author_sort | Omar Tolaymat |
| collection | DOAJ |
| description | Introduction. Diffuse alveolar hemorrhage is a rare presentation of systemic lupus erythematosus. Early diagnosis and appropriate treatment can improve outcome. Case Report. An 18-year-old male presented with hemoptysis and respiratory distress requiring orotracheal intubation. Laboratory tests showed positive anti-nuclear antibody and anti-dsDNA and low C3 and C4. Bronchoalveolar lavage became progressively hemorrhagic after each aliquot. He was treated with pulse methylprednisolone, cyclophosphamide, and plasma exchanges. Discussion. Alveolar hemorrhage is a rare initial presentation of lupus, with mortality rates reported at about 50%. Lupus should be considered in those presenting with alveolar hemorrhage since delay in therapy may cause a rapid deterioration of the patient. The diagnosis of SLE is illusive when DAH is the presenting symptom. Since early diagnosis and appropriate institution of treatment improve outcome, it is important to keep lupus in mind as an etiology of alveolar hemorrhage. Pulse methylprednisolone, cyclophosphamide, and plasmapheresis therapy resulted in rapid improvement of respiratory function in our patient. |
| format | Article |
| id | doaj-art-9d19b9cc335a43d59cd94eecec9de519 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-9d19b9cc335a43d59cd94eecec9de5192025-02-03T01:10:18ZengWileyCase Reports in Rheumatology2090-68892090-68972018-01-01201810.1155/2018/82189048218904Systemic Lupus Erythematosus Presenting with Alveolar HemorrhageOmar Tolaymat0Florentina Berianu1Mayo Clinic Florida, Department of Rheumatology, 4500 San Pablo Road, Jacksonville, FL 32224, USAMayo Clinic Florida, Department of Rheumatology, 4500 San Pablo Road, Jacksonville, FL 32224, USAIntroduction. Diffuse alveolar hemorrhage is a rare presentation of systemic lupus erythematosus. Early diagnosis and appropriate treatment can improve outcome. Case Report. An 18-year-old male presented with hemoptysis and respiratory distress requiring orotracheal intubation. Laboratory tests showed positive anti-nuclear antibody and anti-dsDNA and low C3 and C4. Bronchoalveolar lavage became progressively hemorrhagic after each aliquot. He was treated with pulse methylprednisolone, cyclophosphamide, and plasma exchanges. Discussion. Alveolar hemorrhage is a rare initial presentation of lupus, with mortality rates reported at about 50%. Lupus should be considered in those presenting with alveolar hemorrhage since delay in therapy may cause a rapid deterioration of the patient. The diagnosis of SLE is illusive when DAH is the presenting symptom. Since early diagnosis and appropriate institution of treatment improve outcome, it is important to keep lupus in mind as an etiology of alveolar hemorrhage. Pulse methylprednisolone, cyclophosphamide, and plasmapheresis therapy resulted in rapid improvement of respiratory function in our patient.http://dx.doi.org/10.1155/2018/8218904 |
| spellingShingle | Omar Tolaymat Florentina Berianu Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage Case Reports in Rheumatology |
| title | Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage |
| title_full | Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage |
| title_fullStr | Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage |
| title_full_unstemmed | Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage |
| title_short | Systemic Lupus Erythematosus Presenting with Alveolar Hemorrhage |
| title_sort | systemic lupus erythematosus presenting with alveolar hemorrhage |
| url | http://dx.doi.org/10.1155/2018/8218904 |
| work_keys_str_mv | AT omartolaymat systemiclupuserythematosuspresentingwithalveolarhemorrhage AT florentinaberianu systemiclupuserythematosuspresentingwithalveolarhemorrhage |