Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells

Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells

Abstract MicroRNAs (miRNAs) have been recognised as potential biomarkers due to their specific expression patterns in different biological tissues and their changes in expression under pathological conditions. MicroRNA-122 (miR-122) is a vertebrate-specific miRNA that is predominantly expressed in t...

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Main Authors: Agustín Robles-Remacho, Ismael Martos-Jamai, Mavys Tabraue-Chávez, Araceli Aguilar-González, Jose A. Laz-Ruiz, M. Victoria Cano-Cortés, F. Javier López-Delgado, Juan J. Guardia-Monteagudo, Salvatore Pernagallo, Juan J. Diaz-Mochon, Rosario M. Sanchez-Martin
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
MicroRNA
Microribonucleic acid
miR-122
Click chemistry
Bioorthogonal chemistry
Nanosystem
Online Access:https://doi.org/10.1186/s12951-024-03071-6
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https://doi.org/10.1186/s12951-024-03071-6

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