Phylogenetic divergence of GABAB receptor signaling in neocortical networks over adult life

Abstract Cortical circuit activity is controlled by GABA-mediated inhibition in a spatiotemporally restricted manner. GABAB receptor (GABABR) signalling exerts powerful slow inhibition that controls synaptic, dendritic and neuronal activity. But, how GABABRs contribute to circuit-level inhibition ov...

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Bibliographic Details
Main Authors: Max A. Wilson, Anna Sumera, Lewis W. Taylor, Soraya Meftah, Robert I. McGeachan, Tamara Modebadze, B. Ashan P. Jayasekera, Christopher J. A. Cowie, Fiona E. N. LeBeau, Imran Liaquat, Claire S. Durrant, Paul M. Brennan, Sam A. Booker
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59262-8
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