The Use of Spreadsheets for Pharmacokinetic Simulations

The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands...

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Main Author: Joseph Chamberlain
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2003.02
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author Joseph Chamberlain
author_facet Joseph Chamberlain
author_sort Joseph Chamberlain
collection DOAJ
description The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands, the technique is shown to be applicable to the full range of advanced pharmacokinetic simulations. Demonstrations of the effect of a variety of physiological eventualities are included to show the versatility of the technique. The technique is very simple to use and is always in the complete control of the modeller.
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spelling doaj-art-9ca069c86c8141b5a4ad58caf9fee1b92025-02-03T01:06:51ZengWileyThe Scientific World Journal1537-744X2003-01-01326527810.1100/tsw.2003.02The Use of Spreadsheets for Pharmacokinetic SimulationsJoseph Chamberlain0127 Church Green Road, Bletchley, Milton Keynes, Buckinghamshire, MK3 6DE, UKThe use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands, the technique is shown to be applicable to the full range of advanced pharmacokinetic simulations. Demonstrations of the effect of a variety of physiological eventualities are included to show the versatility of the technique. The technique is very simple to use and is always in the complete control of the modeller.http://dx.doi.org/10.1100/tsw.2003.02
spellingShingle Joseph Chamberlain
The Use of Spreadsheets for Pharmacokinetic Simulations
The Scientific World Journal
title The Use of Spreadsheets for Pharmacokinetic Simulations
title_full The Use of Spreadsheets for Pharmacokinetic Simulations
title_fullStr The Use of Spreadsheets for Pharmacokinetic Simulations
title_full_unstemmed The Use of Spreadsheets for Pharmacokinetic Simulations
title_short The Use of Spreadsheets for Pharmacokinetic Simulations
title_sort use of spreadsheets for pharmacokinetic simulations
url http://dx.doi.org/10.1100/tsw.2003.02
work_keys_str_mv AT josephchamberlain theuseofspreadsheetsforpharmacokineticsimulations
AT josephchamberlain useofspreadsheetsforpharmacokineticsimulations