The Use of Spreadsheets for Pharmacokinetic Simulations
The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands...
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Format: | Article |
Language: | English |
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Wiley
2003-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/tsw.2003.02 |
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author | Joseph Chamberlain |
author_facet | Joseph Chamberlain |
author_sort | Joseph Chamberlain |
collection | DOAJ |
description | The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands, the technique is shown to be applicable to the full range of advanced pharmacokinetic simulations. Demonstrations of the effect of a variety of physiological eventualities are included to show the versatility of the technique. The technique is very simple to use and is always in the complete control of the modeller. |
format | Article |
id | doaj-art-9ca069c86c8141b5a4ad58caf9fee1b9 |
institution | Kabale University |
issn | 1537-744X |
language | English |
publishDate | 2003-01-01 |
publisher | Wiley |
record_format | Article |
series | The Scientific World Journal |
spelling | doaj-art-9ca069c86c8141b5a4ad58caf9fee1b92025-02-03T01:06:51ZengWileyThe Scientific World Journal1537-744X2003-01-01326527810.1100/tsw.2003.02The Use of Spreadsheets for Pharmacokinetic SimulationsJoseph Chamberlain0127 Church Green Road, Bletchley, Milton Keynes, Buckinghamshire, MK3 6DE, UKThe use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands, the technique is shown to be applicable to the full range of advanced pharmacokinetic simulations. Demonstrations of the effect of a variety of physiological eventualities are included to show the versatility of the technique. The technique is very simple to use and is always in the complete control of the modeller.http://dx.doi.org/10.1100/tsw.2003.02 |
spellingShingle | Joseph Chamberlain The Use of Spreadsheets for Pharmacokinetic Simulations The Scientific World Journal |
title | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_full | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_fullStr | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_full_unstemmed | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_short | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_sort | use of spreadsheets for pharmacokinetic simulations |
url | http://dx.doi.org/10.1100/tsw.2003.02 |
work_keys_str_mv | AT josephchamberlain theuseofspreadsheetsforpharmacokineticsimulations AT josephchamberlain useofspreadsheetsforpharmacokineticsimulations |